Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Lnk
Flybase description The gene Lnk is referred to in FlyBase by the symbol Dmel\Lnk (CG17367, FBgn0028717).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.9929 -2.483 -3.252103 -3.2725 -5.653575 -4.2162 -3.22288 -4.489058
    Affimetrix absolute value 6.091 6.313 6.48 6.694 6.263 6.492 6.873 6.114
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: signal transducer activity.
There is experimental evidence that it is involved in the biological process: positive regulation of insulin receptor signaling pathway; female mating behavior; regulation of growth.
14 alleles are reported.
The phenotypes of these alleles are annotated with: eye; ovary; oocyte; wing blade; wing; ommatidium.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Phenylalanine zipper; Pleckstrin homology domain; Pleckstrin homology-type; SH2 motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during early pupal stages, in adult female stages.
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