Flygut: an atlas of the Drosophila adult midgut

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Gene name nAcRalpha-34E
Flybase description The gene nicotinic Acetylcholine Receptor α 34E is referred to in FlyBase by the symbol Dmel\nAcRα-34E (CG32975, FBgn0028875).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -37.5011 -18.6825 -26.462338 -29.8885 -37.453905 -39.0934 -35.7885 -26.499144
    Affimetrix absolute value 3.181 3.406 3.456 3.492 3.543 3.273 3.403 3.602
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: acetylcholine binding; nicotinic acetylcholine-activated cation-selective channel activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ion transport.
9 alleles are reported.
No phenotypic data is available.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site; Nicotinic acetylcholine receptor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages.
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