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Gene name | nAcRalpha-34E | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene nicotinic Acetylcholine Receptor α 34E is referred to in FlyBase by the symbol Dmel\nAcRα-34E (CG32975, FBgn0028875). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: acetylcholine binding; nicotinic acetylcholine-activated cation-selective channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ion transport. 9 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site; Nicotinic acetylcholine receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages. . |