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| Gene name | trbl | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene tribbles is referred to in FlyBase by the symbol Dmel\trbl (CG5408, FBgn0028978). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process: ventral furrow formation; negative regulation of mitosis; regulation of cell cycle. 31 alleles are reported. The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: organ system; multicellular structure; portion of tissue; organ system subdivision; eo support cell; external compound sense organ; adult segment; sense organ; cell cycle; epithelial furrow. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein kinase, catalytic domain; Protein kinase-like domain; Pseudokinase tribbles family/serine-threonine-protein kinase 40; Serine/threonine-protein kinase-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. . |
