Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Spn6
Flybase description The gene Serine protease inhibitor 6 is referred to in FlyBase by the symbol Dmel\Spn6 (CG10913, FBgn0028983).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.366 9.2562 8.668112 6.8523 7.738295 5.6714 -2.71414 7.532713
    Affimetrix absolute value 8.365 10.821 11.288 11.159 11.704 11.046 7.17 11.107
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: serine-type endopeptidase inhibitor activity.
The biological processes in which it is involved are not known.
3 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protease inhibitor I4, serpin; Protease inhibitor I4, serpin, conserved site; Serpin domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period.
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