Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Spn5
Flybase description The gene Serine protease inhibitor 5 is referred to in FlyBase by the symbol Dmel\Spn5 (CG18525, FBgn0028984).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.3721 -5.5686 -22.261741 -18.4621 -32.044238 -16.4861 2.00881 -9.495808
    Affimetrix absolute value 8.358 5.165 3.735 4.2 3.759 4.546 9.501 5.021
    Affymetric present call in "x" number of chips 3 1 0 0 0 0 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: serine-type endopeptidase inhibitor activity.
There is experimental evidence that it is involved in the biological process: negative regulation of Toll signaling pathway.
7 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Protease inhibitor I4, serpin; Protease inhibitor I4, serpin, conserved site; Serpin domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 12-18 embryonic stages, at stages throughout the pupal period.
.