Flygut: an atlas of the Drosophila adult midgut

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Gene name Spn3
Flybase description The gene Serine protease inhibitor 3 is referred to in FlyBase by the symbol Dmel\Spn3 (CG9334, FBgn0028986).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -41.4869 -28.6623 -38.558265 -51.2536 -47.087305 -49.6298 -44.4646 -39.52932
    Affimetrix absolute value 3.048 2.815 2.951 2.725 3.217 2.93 3.11 2.962
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: serine-type endopeptidase inhibitor activity.
There is experimental evidence that it is involved in the biological process: defense response to Gram-negative bacterium; multicellular organism reproduction.
5 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protease inhibitor I4, serpin; Serpin domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of no expression detected.
Peak expression observed in adult male stages.
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