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Gene name | lack | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene lethal with a checkpoint kinase is referred to in FlyBase by the symbol Dmel\lack (CG4943, FBgn0029006). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: decapentaplegic receptor signaling pathway; transforming growth factor beta receptor signaling pathway; embryonic hindgut morphogenesis; embryonic development via the syncytial blastoderm; protein ubiquitination involved in ubiquitin-dependent protein catabolic process; regulation of growth. 11 alleles are reported. The phenotypes of these alleles are annotated with: leg; mesothoracic tergum; wing. It has one annotated transcript and one annotated polypeptide. Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 membrane targeting protein; HECT; WW/Rsp5/WWP. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages. . |