Flygut: an atlas of the Drosophila adult midgut

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Gene name Hml
Flybase description The gene Hemolectin is referred to in FlyBase by the symbol Dmel\Hml (CG7002, FBgn0029167).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -31.0048 -19.7585 -32.0108 -36.1601 -46.323982 -43.8363 -37.90133 -34.846789
    Affimetrix absolute value 3.496 3.323 3.188 3.223 3.234 3.109 3.328 3.203
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein homodimerization activity.
There is experimental evidence that it is involved in the biological process: hemolymph coagulation; hemostasis; wound healing.
5 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Chitin binding domain; Coagulation factor 5/8 type, C-terminal; Cystine knot, C-terminal; EGF-like region, conserved site; Epidermal growth factor-like; Epidermal growth factor-like, type 3; Galactose-binding domain-like; Hemolectin/hemocytin; Low-density lipoprotein (LDL) receptor class A repeat; Protease inhibitor I8, cysteine-rich trypsin inhibitor-like; Sushi/SCR/CCP; Uncharacterised domain, cysteine-rich; von Willebrand factor, type C; von Willebrand factor, type D domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed at stages throughout the larval period.
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