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Gene name | CHES-1-like | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Checkpoint suppressor homologue is referred to in FlyBase by the symbol Dmel\CHES-1-like (CG12690, FBgn0029504). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: cellular response to hypoxia; mitotic cell cycle G1/S transition DNA damage checkpoint; phagocytosis, engulfment. 30 alleles are reported. The phenotypes of these alleles are annotated with: eye; heart primordium. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Armadillo-like helical; Transcription factor, fork head; Transcription factor, fork head, conserved site; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. . |