Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG3446
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG3446 (FBgn0029868).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 5.9952 6.181 4.075557 4.3707 2.381813 3.7717 7.14487 3.74527
    Affimetrix absolute value 10.99 10.235 10.142 10.515 9.985 10.474 11.383 10.048
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: NADH dehydrogenase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: mitochondrial electron transport, NADH to ubiquinone.
2 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: GRIM-19.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in stages of adults of both sexes.
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