Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Marf
Flybase description The gene Mitochondrial assembly regulatory factor is referred to in FlyBase by the symbol Dmel\Marf (CG3869, FBgn0029870).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.1119 2.0878 1.456114 1.6247 -1.263324 0.3891 1.85954 0.351382
    Affimetrix absolute value 8.556 8.674 8.698 9.073 8.43 8.637 9.429 8.284
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity.
There is experimental evidence that it is involved in the biological process: mitochondrion organization.
6 alleles are reported.
The phenotypes of these alleles are annotated with: mitochondrial crista; trichogen cell; mitochondrion; indirect flight muscle.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Dynamin, GTPase domain; Fzo/mitofusin HR2 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.
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