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Gene name | Pink1 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene PTEN-induced putative kinase 1 is referred to in FlyBase by the symbol Dmel\Pink1 (CG4523, FBgn0029891). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: protein kinase activity. There is experimental evidence that it is involved in the biological process: negative regulation of programmed cell death; mitochondrial fission; sperm mitochondrion organization; negative regulation of neuron apoptosis; compound eye development; response to oxidative stress; regulation of mitochondrion organization; mitochondrion organization. 21 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; organ system subdivision; cytoplasmic part; adult; organelle; external compound sense organ; adult segment; intracellular organelle; spermatozoon; elongation stage spermatid. It has 8 annotated transcripts and 8 annotated polypeptides. Protein features are: Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed in adult male stages. . |