Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name slpr
Flybase description The gene slipper is referred to in FlyBase by the symbol Dmel\slpr (CG2272, FBgn0030018).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.2558 -3.0923 -5.847924 -4.1965 -9.149235 -5.7275 -6.81043 -8.169804
    Affimetrix absolute value 5.764 6.003 5.717 6.341 5.664 6.059 5.822 5.316
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: JUN kinase kinase kinase activity; protein kinase activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; post-embryonic organ morphogenesis; instar larval or pupal morphogenesis; cellular component organization or biogenesis; macromolecule modification; genital disc development; system development; phosphorus metabolic process; response to organic substance; ovarian follicle cell development; development of primary male sexual characteristics; positive regulation of MAPKKK cascade.
29 alleles are reported.
The phenotypes of these alleles are annotated with: maxillary palpus; embryonic/first instar larval cuticle; dorsal closure embryo; male terminalia; mesothoracic tergum; wing; embryonic dorsal epidermis; female terminalia; scutellum; embryonic leading edge cell.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Mitogen activated protein kinase kinase kinase 9/10/11-like; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Serine/threonine-protein kinase, active site; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
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