| Home | Overview of gut regions | Anatomy | Histology | Transgene expression mapping | Gene expression |
| Search expression data by gene: |
| Gene name | PGRP-SA | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Peptidoglycan recognition protein SA is referred to in FlyBase by the symbol Dmel\PGRP-SA (CG11709, FBgn0030310). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
|
||||||||||||||||||||||||||||||||||||
| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
||||||||||||||||||||||||||||||||||||
| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; muramyl dipeptide binding; peptidoglycan binding. There is experimental evidence that it is involved in the biological process: defense response to Gram-positive bacterium; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria; response to peptidoglycan. 17 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria; Peptidoglycan recognition protein, PGRP-S. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during early pupal stages. . |
