Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG1837
Flybase description The gene pretaporter is referred to in FlyBase by the symbol Dmel\prtp (CG1837, FBgn0030329).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.2996 2.3754 3.429262 4.55 2.67492 2.6049 -0.44924 3.156296
    Affimetrix absolute value 8.45 8.865 9.953 10.564 10.175 9.935 8.406 9.883
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein disulfide isomerase activity.
There is experimental evidence that it is involved in the biological process: apoptotic cell clearance.
9 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval glial cell; embryonic hemocyte.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Disulphide isomerase; Thioredoxin; Thioredoxin domain; Thioredoxin, conserved site; Thioredoxin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-12 hour embryonic stages, during late larval stages, during early pupal stages.
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