Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name NFAT
Flybase description The gene NFAT homolog is referred to in FlyBase by the symbol Dmel\NFAT (CG11172, FBgn0030505).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -65.9109 -37.7368 -56.715224 -72.7893 -91.879332 -82.0174 -67.20898 -76.360053
    Affimetrix absolute value 2.379 2.403 2.39 2.214 2.244 2.205 2.483 2.064
    Affymetric present call in "x" number of chips 2 2 2 2 2 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: negative regulation of synaptic vesicle exocytosis; response to salt stress.
49 alleles are reported.
The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system subdivision; organ system; adult segment; peripheral nervous system; embryonic/larval neuron; synapse; integumentary plate; thoracic segment; eo support cell; embryonic/larval anal pad; external compound sense organ.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Armadillo-like helical; Cell surface receptor IPT/TIG; Immunoglobulin E-set; Immunoglobulin-like fold; Nuclear factor of activated T cells (NFAT); Rel homology; p53-like transcription factor, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.
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