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| Gene name | Lig4 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Ligase4 is referred to in FlyBase by the symbol Dmel\Lig4 (CG12176, FBgn0030506). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: telomere maintenance; response to ionizing radiation; double-strand break repair via nonhomologous end joining. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: BRCT; DNA ligase, ATP-dependent; DNA ligase, ATP-dependent, C-terminal; DNA ligase, ATP-dependent, N-terminal; DNA ligase, ATP-dependent, central; Nucleic acid-binding, OB-fold; Nucleic acid-binding, OB-fold-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes. . |
