Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG8184
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG8184 (FBgn0030674).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -8.5912 -2.3006 -4.098021 -5.3335 -8.361085 -5.5921 -5.61725 -7.405434
    Affimetrix absolute value 5.324 6.417 6.195 6.034 5.76 6.079 6.11 5.406
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ubiquitin-protein ligase activity.
There is experimental evidence that it is involved in the biological process: dsRNA transport.
One allele is reported.
The phenotype of this allele is annotated with: mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Armadillo-like helical; E3 ubiquitin ligase, domain of unknown function DUF908; E3 ubiquitin ligase, domain of unknown function DUF913; HECT; UBA-like; Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote; WWE domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, during early pupal stages, in stages of adults of both sexes.
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