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Gene name | PGRP-LE | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Peptidoglycan recognition protein LE is referred to in FlyBase by the symbol Dmel\PGRP-LE (CG8995, FBgn0030695). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: immune response; response to bacterium; determination of adult lifespan; defense response to Gram-positive bacterium; positive regulation of innate immune response; defense response to bacterium. 5 alleles are reported. The phenotypes of these alleles are annotated with: adult cuticle; melanotic mass. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: N-acetylmuramoyl-L-alanine amidase domain; Peptidoglycan recognition protein; Peptidoglycan recognition protein family domain, metazoa/bacteria. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages. . |