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Gene name | HERC2 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene HERC2 is referred to in FlyBase by the symbol Dmel\HERC2 (CG11734, FBgn0031107). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: ubiquitin-protein ligase activity; guanyl-nucleotide exchange factor activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: protein ubiquitination. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Anaphase-promoting complex, subunit 10/DOC domain; CPH domain; CUB; Cytochrome b5; Galactose-binding domain-like; HECT; Mib-herc2; Regulator of chromosome condensation, RCC1; Regulator of chromosome condensation/beta-lactamase-inhibitor protein II; Translation protein SH3-like, subgroup; UBA-like; Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages. . |