Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Ent1
Flybase description The gene Equilibrative nucleoside transporter 1 is referred to in FlyBase by the symbol Dmel\Ent1 (CG11907, FBgn0031250).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.6773 -2.1918 -3.519705 -3.0386 -3.360695 -1.7501 -2.50918 -3.386184
    Affimetrix absolute value 7.717 6.499 6.373 6.791 7.034 7.756 7.243 6.52
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: nucleoside transmembrane transporter activity.
Based on sequence similarity, it is predicted to be involved in the biological process: nucleoside transport.
3 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; scutellar bristle; wing.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Delayed-early response protein/equilibrative nucleoside transporter; Major facilitator superfamily domain, general substrate transporter.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed during late larval stages, during early pupal stages.
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