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| Gene name | Spp | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Signal peptide protease is referred to in FlyBase by the symbol Dmel\Spp (CG11840, FBgn0031260). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: aspartic endopeptidase activity, intramembrane cleaving. There is experimental evidence that it is involved in the biological process: membrane protein proteolysis; open tracheal system development. 16 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; heart primordium; embryonic/larval tracheal system. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase A22, presenilin signal peptide; Peptidase A22B, signal peptide peptidase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages. . |
