Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name ia2
Flybase description The gene IA-2 ortholog is referred to in FlyBase by the symbol Dmel\IA-2 (CG31795, FBgn0031294).
Expression data along the gut
    Created with Highcharts 6.0.3Fold change compared to full gutRegion-specific expression of ia2 along the gutCropCardia/R1R2R3R4R5Hindgut-2-1012Highcharts.com
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -38.9943 -21.607 -27.113987 -36.1334 -45.75492 -38.7187 -41.78765 -32.731739
    Affimetrix absolute value 3.133 3.2 3.457 3.216 3.269 3.292 3.17 3.254
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Created with Highcharts 6.0.3Fold change compared toUnchallengedFold change compared to UnchallengedExpression of ia2 in different experimental conditionsEcc15 4hEcc15 16hPe 4hPe 16hPe gacA 4hPe gacA 16h-3-2-1012Highcharts.com
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: transmembrane receptor protein tyrosine phosphatase activity.
It is reported to be involved in the biological process: protein dephosphorylation.
8 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Protein-tyrosine phosphatase, receptor/non-receptor type; Protein-tyrosine/Dual-specificity phosphatase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
.