Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name AIF
Flybase description The gene Apoptosis inducing factor is referred to in FlyBase by the symbol Dmel\AIF (CG7263, FBgn0031392).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.5591 -1.5271 -1.428234 -1.6526 -2.184679 -1.6852 -1.80573 -2.135082
    Affimetrix absolute value 6.244 7.01 7.674 7.67 7.639 7.812 7.713 7.23
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: oxidoreductase activity; flavin adenine dinucleotide binding.
There is experimental evidence that it is involved in the biological process: regulation of programmed cell death; mitochondrion organization.
9 alleles are reported.
The phenotypes of these alleles are annotated with: eye disc; eye; trichogen cell; ventral nerve cord; Bolwig organ; ommatidium; mesothoracic bristle.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD/NAD-linked reductase, dimerisation; Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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