Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name lid
Flybase description The gene little imaginal discs is referred to in FlyBase by the symbol Dmel\lid (CG9088, FBgn0031759).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.6635 -1.8193 -3.774017 -3.4898 -8.150261 -4.6161 -3.14043 -6.742179
    Affimetrix absolute value 5.497 6.758 6.329 6.603 5.822 6.363 6.935 5.669
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: histone acetyltransferase activity (H3-K9 specific); protein binding; histone demethylase activity (H3-trimethyl-K4 specific); histone demethylase activity (H3-K4 specific).
There is experimental evidence that it is involved in the biological process: chromatin organization; histone H3-K9 acetylation; histone H3-K4 demethylation.
25 alleles are reported.
The phenotypes of these alleles are annotated with: mesothoracic tergum; imaginal disc; embryonic/larval optic lobe.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: ARID/BRIGHT DNA-binding domain; Lysine-specific demethylase-like domain; Transcription factor jumonji; Transcription factor jumonji, JmjN; Transcription factor jumonji/aspartyl beta-hydroxylase; Zinc finger, C5HC2-type; Zinc finger, FYVE/PHD-type; Zinc finger, PHD-finger; Zinc finger, PHD-type; Zinc finger, PHD-type, conserved site; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, in adult female stages.
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