Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Fbw5
Flybase description This gene is referred to in FlyBase by the symbol Dmel\Fbw5 (CG9144, FBgn0031773).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.8806 -3.3882 -4.87196 -4.129 -8.019675 -6.1461 -6.54711 -6.923706
    Affimetrix absolute value 6.14 5.858 5.932 6.345 5.806 5.956 5.854 5.506
    Affymetric present call in "x" number of chips 3 3 2 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
Based on sequence similarity, it is predicted to be involved in the biological process: protein ubiquitination involved in ubiquitin-dependent protein catabolic process.
4 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: F-box domain, Skp2-like; F-box domain, cyclin-like; WD40 repeat; WD40 repeat 2; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
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