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Gene name | r2d2 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene r2d2 is referred to in FlyBase by the symbol Dmel\r2d2 (CG7138, FBgn0031951). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: double-stranded RNA binding. There is experimental evidence that it is involved in the biological process: production of small RNA involved in gene silencing by RNA; siRNA loading onto RISC involved in RNA interference; heterochromatin organization involved in chromatin silencing; ovarian follicle cell stalk formation; production of siRNA involved in RNA interference; defense response to virus; regulation of production of small RNA involved in gene silencing by RNA. 18 alleles are reported. The phenotypes of these alleles are annotated with: interfollicle cell; trichogen cell; follicle cell; egg chamber. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Double-stranded RNA-binding; Double-stranded RNA-binding-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages. . |