Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG5853
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG5853 (FBgn0032167).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.5813 -3.3983 -0.420646 2.5303 2.190626 11.6116 -2.40397 2.454035
    Affimetrix absolute value 8.68 5.857 8.102 9.726 9.732 12.058 7.486 9.39
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled to transmembrane movement of substances; transporter activity.
There is experimental evidence that it is involved in the biological process: phagocytosis, engulfment.
8 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: ABC transporter, G1-like; ABC transporter, conserved site; ABC transporter-like; ABC-2 type transporter; ATPase, AAA+ type, core.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 18-24 hour embryonic stages, during early pupal stages.
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