Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG4839
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG4839 (FBgn0032187).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -37.3865 -1.5216 -1.697839 -2.3699 -3.76402 -2.7499 -33.00299 -3.329338
    Affimetrix absolute value 3.217 7.028 7.479 7.164 6.9 7.103 3.551 6.603
    Affymetric present call in "x" number of chips 0 3 3 3 3 3 1 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: cGMP-dependent protein kinase activity.
It is reported to be involved in the biological process: protein phosphorylation.
4 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: AGC-kinase, C-terminal; Cyclic nucleotide-binding domain; Cyclic nucleotide-binding, conserved site; Cyclic nucleotide-binding-like; Protein kinase, catalytic domain; Protein kinase-like domain; RmlC-like jelly roll fold; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages.
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