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Gene name | CYLD | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene cylindromatosis is referred to in FlyBase by the symbol Dmel\CYLD (CG5603, FBgn0032210). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: ubiquitin-specific protease activity. There is experimental evidence that it is involved in the biological process: protein deubiquitination; stress-activated protein kinase signaling cascade; determination of adult lifespan; response to oxidative stress; defense response to bacterium; acylglycerol homeostasis. 15 alleles are reported. The phenotypes of these alleles are annotated with: adult fat body; lipid particle; scutellum. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Cytoskeleton-associated protein, Gly-rich domain; Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2; Ribosomal protein S3Ae. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 12-18 embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages. . |