Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Tom70
Flybase description The gene Translocase of outer membrane 70 is referred to in FlyBase by the symbol Dmel\Tom70 (CG6756, FBgn0032397).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.6706 -4.1911 -4.686936 -3.2391 -6.946979 -4.5891 -4.12423 -6.256989
    Affimetrix absolute value 4.649 5.554 5.97 6.693 6.012 6.366 6.506 5.679
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: P-P-bond-hydrolysis-driven protein transmembrane transporter activity.
Based on sequence similarity, it is predicted to be involved in the biological process: protein targeting to mitochondrion.
3 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Tetratricopeptide TPR-3; Tetratricopeptide TPR2; Tetratricopeptide repeat; Tetratricopeptide repeat-containing; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in adult male stages.
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