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| Gene name | MRP | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Multidrug-Resistance like Protein 1 is referred to in FlyBase by the symbol Dmel\MRP (CG6214, FBgn0032456). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: ATPase activity, coupled to movement of substances; ATPase activity, coupled to transmembrane movement of substances. There is experimental evidence that it is involved in the biological process: response to methotrexate. 7 alleles are reported. No phenotypic data is available. It has 17 annotated transcripts and 17 annotated polypeptides. Protein features are: ABC transporter, conserved site; ABC transporter, integral membrane type 1; ABC transporter, transmembrane domain; ABC transporter, transmembrane domain, type 1; ABC transporter-like; ATPase, AAA+ type, core; Multi drug resistance-associated protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in stages of adults of both sexes. . |
