Flygut: an atlas of the Drosophila adult midgut

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Gene name CG8665
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG8665 (FBgn0032945).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -19.4479 -8.0553 -9.985612 -8.35 -15.548593 -13.8862 -17.3773 -13.159971
    Affimetrix absolute value 4.135 4.611 4.858 5.331 4.812 4.768 4.443 4.568
    Affymetric present call in "x" number of chips 0 0 1 3 1 3 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: formyltetrahydrofolate dehydrogenase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process; one-carbon metabolic process; 10-formyltetrahydrofolate catabolic process; biosynthetic process.
4 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: 10-formyltetrahydrofolate dehydrogenase; Acyl carrier protein-like; Aldehyde dehydrogenase domain; Aldehyde dehydrogenase, C-terminal; Aldehyde dehydrogenase, N-terminal; Aldehyde dehydrogenase, conserved site; Aldehyde/histidinol dehydrogenase; Formyl transferase, C-terminal; Formyl transferase, C-terminal-like; Formyl transferase, N-terminal; Phosphopantetheine-binding; Phosphoribosylglycinamide formyltransferase, active site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed during late larval stages.
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