Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Cul-2
Flybase description The gene Cullin-2 is referred to in FlyBase by the symbol Dmel\Cul-2 (CG1512, FBgn0032956).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.4449 -1.8885 -3.671691 -2.3205 -5.702181 -3.1603 -2.95532 -5.039601
    Affimetrix absolute value 7.132 6.722 6.321 7.177 6.298 6.903 7.005 6.009
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: ubiquitin protein ligase binding.
There is experimental evidence that it is involved in the biological process: neurogenesis.
9 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Cullin homology; Cullin protein, neddylation domain; Cullin repeat-like-containing domain; Cullin, N-terminal; Cullin, conserved site; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
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