Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name CG11198
Flybase description The gene Acetyl-CoA carboxylase is referred to in FlyBase by the symbol Dmel\ACC (CG11198, FBgn0033246).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 4.7977 5.0821 -0.51786 -2.2731 -5.941745 -1.5079 1.80917 -0.921508
    Affimetrix absolute value 10.662 9.94 7.973 7.216 6.273 7.972 9.363 7.711
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: acetyl-CoA carboxylase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: fatty acid biosynthetic process.
5 alleles are reported.
No phenotypic data is available.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: ATP-grasp fold; ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; Acetyl-CoA carboxylase, central domain; Acetyl-coenzyme A carboxyltransferase, C-terminal; Acetyl-coenzyme A carboxyltransferase, N-terminal; Biotin carboxylase, C-terminal; Biotin carboxylation domain; Biotin-binding site; Biotin/lipoyl attachment; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carboxyl transferase; Pre-ATP-grasp fold; PreATP-grasp-like fold; Rudiment single hybrid motif; Single hybrid motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed within 18-24 hour embryonic stages.
.