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Gene name | Myd88 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Myd88 is referred to in FlyBase by the symbol Dmel\Myd88 (CG2078, FBgn0033402). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; Toll binding. There is experimental evidence that it is involved in the biological process: defense response to fungus; dorsal/ventral pattern formation; Toll signaling pathway; defense response to Gram-positive bacterium; antifungal peptide production; positive regulation of antifungal peptide production. 55 alleles are reported. The phenotypes of these alleles are annotated with: filzkorper; denticle belt. It has one annotated transcript and one annotated polypeptide. Protein features are: DEATH-like; Toll-Interleukin receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early pupal stages. . |