Flygut: an atlas of the Drosophila adult midgut

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Gene name Mmp2
Flybase description The gene Matrix metalloproteinase 2 is referred to in FlyBase by the symbol Dmel\Mmp2 (CG1794, FBgn0033438).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -33.5585 -11.6241 -13.213101 -20.5986 -24.903056 -21.7121 -47.07899 -21.465706
    Affimetrix absolute value 3.385 4.109 4.501 4.099 4.182 4.341 2.995 3.846
    Affymetric present call in "x" number of chips 1 1 1 1 1 1 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: metalloendopeptidase activity.
There is experimental evidence that it is involved in the biological process: tracheal pit formation in open tracheal system; negative regulation of fibroblast growth factor receptor signaling pathway; lateral inhibition; basement membrane disassembly; tracheal outgrowth, open tracheal system; imaginal disc fusion, thorax closure; imaginal disc eversion; basement membrane organization; oogenesis; open tracheal system development.
118 alleles are reported.
The phenotypes of these alleles are annotated with: interommatidial bristle; adult thorax; ommatidium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Hemopexin/matrixin; Hemopexin/matrixin, repeat; Metallopeptidase, catalytic domain; Peptidase M10, metallopeptidase; Peptidase M10A, matrix metallopeptidase; Peptidase, metallopeptidase; Peptidoglycan binding-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed during early pupal stages.
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