Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pyr
Flybase description The gene pyramus is referred to in FlyBase by the symbol Dmel\pyr (CG13194, FBgn0033649).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.0605 -4.9611 -16.076589 -5.2089 -29.171722 -12.7072 -5.74784 -15.164467
    Affimetrix absolute value 7.397 5.313 4.175 6.006 3.928 4.9 6.045 4.427
    Affymetric present call in "x" number of chips 3 3 2 3 0 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: fibroblast growth factor receptor binding.
There is experimental evidence that it is involved in the biological process: hindgut morphogenesis; heart development; larval somatic muscle development; glial cell migration; mesoderm migration involved in gastrulation; cardioblast differentiation; positive regulation of glial cell proliferation; pericardial cell differentiation; mesoderm development.
12 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic cardioblast; glial cell; A1-7 ventral oblique muscle 4; A1-7 ventral oblique muscle 6; embryonic dorsal vessel; mesoderm; embryonic somatic muscle; segment border muscle; A1-7 ventral oblique muscle 5.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cytokine, IL-1-like; Interleukin 1/heparin-binding growth factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages, in adult male stages.
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