Flygut: an atlas of the Drosophila adult midgut

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Gene name Den1
Flybase description The gene Deneddylase 1 is referred to in FlyBase by the symbol Dmel\Den1 (CG8493, FBgn0033716).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.5316 -2.1237 -2.968941 -2.6463 -4.260954 -3.5015 -2.69242 -3.123432
    Affimetrix absolute value 7.795 6.533 6.613 6.985 6.669 6.754 7.135 6.613
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: NEDD8-specific protease activity.
There is experimental evidence that it is involved in the biological process: protein deneddylation; positive regulation of apoptosis.
10 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Peptidase C48, SUMO/Sentrin/Ubl1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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