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Gene name | Drl-2 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Derailed 2 is referred to in FlyBase by the symbol Dmel\Drl-2 (CG3915, FBgn0033791). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: receptor signaling protein tyrosine kinase activity. There is experimental evidence that it is involved in the biological process: Wnt receptor signaling pathway; salivary gland morphogenesis. 10 alleles are reported. The phenotypes of these alleles are annotated with: presumptive embryonic salivary gland; antennal lobe glomerulus VL1; glomerulus; antennal lobe glomerulus VM7; antennal lobe. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; WIF domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages. . |