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Gene name | O-fut1 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene O-fucosyltransferase 1 is referred to in FlyBase by the symbol Dmel\O-fut1 (CG12366, FBgn0033901). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: Notch binding; fucosyltransferase activity. There is experimental evidence that it is involved in the biological process: negative regulation of Notch signaling pathway; endocytosis; lateral inhibition; regulation of Notch signaling pathway; cell-cell adhesion; nervous system development; protein catabolic process. 31 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; leg; eye; S2 cell-line; chaeta; wing; wing vein. It has one annotated transcript and one annotated polypeptide. Protein features are: GDP-fucose protein O-fucosyltransferase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, during early pupal stages. . |