Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pcs
Flybase description The gene parcas is referred to in FlyBase by the symbol Dmel\pcs (CG7761, FBgn0033988).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.1496 -1.9833 -3.404583 -4.0484 -7.818241 -4.8595 -4.2419 -5.077062
    Affimetrix absolute value 6.411 6.641 6.452 6.384 5.839 6.289 6.48 5.972
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: SH3 domain binding; protein tyrosine kinase inhibitor activity.
There is experimental evidence that it is involved in the biological process: muscle cell fate specification; muscle organ morphogenesis; muscle organ development; anterior/posterior pattern formation; mesoderm development.
13 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; embryonic head; embryonic abdomen; muscle founder cell; presumptive embryonic/larval muscle system; germline cell; somatic muscle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: SH3-binding 5.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.
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