Flygut: an atlas of the Drosophila adult midgut

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Gene name unc-5
Flybase description The gene unc-5 is referred to in FlyBase by the symbol Dmel\unc-5 (CG8166, FBgn0034013).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -43.825 -27.2266 -41.49712 -46.2425 -61.531336 -51.3194 -51.31016 -50.685216
    Affimetrix absolute value 2.965 2.858 2.808 2.861 2.821 2.881 2.878 2.593
    Affymetric present call in "x" number of chips 0 0 1 0 0 1 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: netrin receptor activity involved in chemorepulsion; netrin receptor activity.
There is experimental evidence that it is involved in the biological process: motor axon guidance; salivary gland boundary specification; axon guidance; glial cell migration.
22 alleles are reported.
The phenotypes of these alleles are annotated with: presumptive embryonic salivary gland; ventral nerve cord commissure; ventral nerve cord; posterior commissure; intersegmental nerve; interface glial cell; longitudinal connective; abdominal segmental nerve; embryonic/larval neuron; anterior commissure.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DEATH-like; Death; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Thrombospondin, type 1 repeat; ZU5.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.
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