Flygut: an atlas of the Drosophila adult midgut

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Gene name Dcr-2
Flybase description The gene Dicer-2 is referred to in FlyBase by the symbol Dmel\Dcr-2 (CG6493, FBgn0034246).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.4982 0.2824 -2.762825 -0.3711 -4.730569 -2.0187 -2.77853 -3.066505
    Affimetrix absolute value 6.608 7.558 6.789 8.336 6.609 7.554 7.108 6.738
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: ATPase activity; siRNA binding.
There is experimental evidence that it is involved in the biological process: siRNA loading onto RISC involved in RNA interference; detection of virus; RNA interference; locomotory behavior; dsRNA transport; heterochromatin organization involved in chromatin silencing; production of siRNA involved in RNA interference; targeting of mRNA for destruction involved in RNA interference; defense response to virus; chromatin silencing.
30 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Argonaute/Dicer protein, PAZ; DEAD-like helicase; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Dicer double-stranded RNA-binding fold; Double-stranded RNA-binding; Helicase, C-terminal; Ribonuclease III.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.
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