| Home | Overview of gut regions | Anatomy | Histology | Transgene expression mapping | Gene expression |
| Search expression data by gene: |
| Gene name | CG4966 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Hermansky-Pudlak Syndrome 4 ortholog is referred to in FlyBase by the symbol Dmel\HPS4 (CG4966, FBgn0034261). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
|
||||||||||||||||||||||||||||||||||||
| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
||||||||||||||||||||||||||||||||||||
| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: odorant binding; thymidylate synthase (FAD) activity; flavin adenine dinucleotide binding. There is experimental evidence that it is involved in the biological process: miRNA loading onto RISC involved in gene silencing by miRNA; negative regulation of gene silencing by RNA; siRNA loading onto RISC involved in chromatin silencing by small RNA. 11 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Pheromone/general odorant binding protein, PBP/GOBP; Thymidylate synthase complementing protein ThyX. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. . |
