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| Gene name | Atg7 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Autophagy-specific gene 7 is referred to in FlyBase by the symbol Dmel\Atg7 (CG5489, FBgn0034366). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: catalytic activity; nucleotide binding. There is experimental evidence that it is involved in the biological process: determination of adult lifespan; macroautophagy; regulation of defense response to virus; regulation of autophagy; autophagy; larval midgut cell programmed cell death. 11 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; egg; adult brain. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: E1-like protein-activating enzyme Gsa7p/Apg7p; Molybdenum cofactor biosynthesis, MoeB; NAD(P)-binding domain; UBA/THIF-type NAD/FAD binding fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed during late larval stages, during early pupal stages. . |
