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Gene name | rad50 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene rad50 is referred to in FlyBase by the symbol Dmel\rad50 (CG6339, FBgn0034728). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: nuclease activity; zinc ion binding; ATP binding. There is experimental evidence that it is involved in the biological process: instar larval development; response to DNA damage stimulus; telomere maintenance; chromosome organization; telomere capping. 6 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye; wing disc; chromosome, telomeric region; chaeta; condensed chromosome; wing. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Haemolysin E; Rad50 zinc hook; Recombination/repair protein Rad50; Zinc hook, Rad50. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. . |