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Gene name | CG11299 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Sestrin is referred to in FlyBase by the symbol Dmel\Sesn (CG11299, FBgn0034897). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: inter-male aggressive behavior; regulation of reactive oxygen species metabolic process; mitochondrion degradation; multicellular organismal aging; negative regulation of cell growth. 12 alleles are reported. The phenotypes of these alleles are annotated with: Z disc; myofibril; actomyosin; wing blade; sarcomere; mitochondrion; M band. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: PA26 p53-induced protein (sestrin). Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed at stages throughout the pupal period. . |