Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name MAN1
Flybase description The gene MAN1 is referred to in FlyBase by the symbol Dmel\MAN1 (CG3167, FBgn0034962).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.3948 -2.9336 -5.269842 -4.6021 -7.459195 -4.6897 -5.40713 -6.17962
    Affimetrix absolute value 6.653 6.066 5.817 6.195 5.882 6.344 6.138 5.668
    Affymetric present call in "x" number of chips 3 3 3 3 2 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: negative regulation of BMP signaling pathway.
13 alleles are reported.
The phenotypes of these alleles are annotated with: posterior crossvein; ovary; anterior crossvein; wing vein L4; testis; wing blade; wing; wing vein.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Inner nuclear membrane protein MAN1; LEM-like domain; Lamino-associated polypeptide 2/emerin.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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