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Gene name | yki | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene yorkie is referred to in FlyBase by the symbol Dmel\yki (CG4005, FBgn0034970). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process: cell proliferation; morphogenesis of an epithelial sheet; negative regulation of apoptosis; stem cell proliferation; cell competition in a multicellular organism; regulation of growth. 53 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; eye; wing disc; follicle cell; wing; adherens junction. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: WW/Rsp5/WWP. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages. . |